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And PE is able to establish hydrogen bonds with a variety of amino acid residues, which in turn inhibits the localization of negative amino acids on the cytoplasmic side, and is an important determinant of the topology of transmembrane structural domains of membrane proteins (Shi et al., 2024)

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Functional genomics approaches indicate that disruption of the functional cell-wall bound GGT1 isoform results in a constitutive alert response where anti-oxidative enzymes are up-regulated, probably as an effect of the altered plasma membrane receptors level and the redox state