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Primarily, the redox state of these thiol groups is controlled by the oxidoreductases of the thioredoxin (Trx) family, to which Trxs, glutaredoxins (Grxs), and peroxiredoxins (Prxs) belong [1,2]

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At the same time, we observed that the enzymatic activities of OXPHOS complexes (complexes I, II, III, and IV) are reduced in the skeletal muscle of SLD chickens and GHR knockdown cells, indicating that GHR exhibits a positive effect on mitochondrial biogenesis